1) You've Got Gut Issues
Did you know the bacteria in your gut can predispose you to gain weight? 
Certain types of gut bacteria produce beta-glucuronidase enzymes that can re-activate (or deconjugate) estrogens that were already detoxified (conjugated) and on their way out of the body leading to estrogen dominance. Decreasing levels of beta-glucuronidase enzyme producing bacteria in your gut is key to stopping the cycle of estrogen recirculation, as well as estrogen's impact on weight. 
Balancing your gut and supporting your digestion should be a top priority by way of prebiotics, certain probiotics, digestive support agents, and antimicrobial agents that are specifically targeted to your own gut imbalances.
My favorite way to assess beta-glucuronidase levels as well as the gut microbiome is the GI Map test.
2) Your cells are not healthy
One of the first steps to healthy weight loss should be creating healthy cells.
A biggie here is cellular inflammation (!). When your cells are inflamed (you have 30 trillion cells in your body) from unhealthy cell membranes, your cells tend to retain more water and weight loss can be an uphill battle.
What impacts cellular health in a big way? Fatty acid balance, specifically your omega 3 to omega 6 ratio. In fact, an imbalanced omega 3:6 ratio is actually linked to obesity. 
Support your cells by increasing omega 3 fats in your diet from low mercury seafood as well as reducing your intake of omega 6 fatty acids like those found in processed oils such as soy, canola, and man-made other vegetable oils.
Want to assess your fatty acid balance? You can learn more about testing here.
3) Your body is operating from an energy deficit.
When there is a chronic energy deficit (fewer calories coming in than going out), over time the body starts thinking food is scarce. This results in the body holding on to fat as a way to protect itself.
To make an analogy, think of your body like a house. If you're not making enough money to pay your electricity bill, what do you do? Well, you turn down the heat in your house to compensate. The body operates in a similar way. When there are not enough calories coming in, the body saves energy by reducing body temperature (slowing the metabolism), turning down digestive juices (making digestion weaker), reducing the pulse, and slowing thyroid function (resulting in less energy).
This is a built-in survival response by the body, to help you go longer on less food that is often induced through calorie counting and dieting.
4) You've cut out carbs and/or sugars.
When you’re not eating enough of the right carbohydrates that are essential to stimulating your metabolism and the conversion of thyroid hormone (T4 to T3) in the liver, weight loss is unlikely. Without an adequate store of carbohydrates (glycogen) in the liver, the body will not make enough of this very important thyroid conversion.
An easy way to self-check yourself is by taking your body temperature (using this) first thing when you wake up in the morning. If it's lower than 97.8 degrees upon waking, your inability to lose weight is probably related to #3 and/or #4.
Get Healthy to Support Weight Homeostasis
The fact that you can't short-cut to weight loss, should be no surprise. It should only come after the body is healthy enough to do it naturally.
As Diana Schwarzbein wisely says, "You need to be healthy to lose weight, not lose weight to be healthy."
And don't forget to make sure your mindset isn't what's keeping you from success. This quick read will let you know right away.
How to get back on track?
My e-book: Creating Wealth: The cure to nutritional debt is designed to get your body and metabolism back on track so you can conquer your weight loss goals while avoiding restrictive dieting! Read more about it here so you can get healthy to lose weight naturally!
Need even MORE help navigating your weight gain?
Subscribe below to gain instant access to my interview: Why Your Metabolism Was Fast, But Now It's Slow. You'll learn a ton of my best metabolism boosting strategies!
Are these problems stopping you from losing weight? Please share in the comments!